ROSADUPLI

Since Ohno's work in 1970, it has been widely accepted that gene duplication is an important factor in the evolution of species, particularly in angiosperms. This hypothesis was reinforced in the 2000s with the sequencing of complete genomes, which showed that genome duplication is a driver of genetic innovation in eukaryote organisms, both plants and animals. However, how duplicated genes evolve and settle in a genome remains a central question in molecular evolution.
We hypothesize that the fate of duplicated genes varies according to the nature of the duplication (complete ancestral whole genome duplication - WGD, tandem duplication or dispersed duplication). We propose to explore this hypothesis systematically in Rosaceae. 
We have developed ROSADUPLI database containing all the gene families in the genomes of apple, pear, peach, wild strawberry, domesticated strawberry and Arabidopsis (as an outgroup), together with the nature of the duplications that led to the expansion of the families.

Funding : Univ. Angers, INRAE

PhD : T. LALLEMAND, M. LEDUC, A. BOUANICH 

Collaborations : N. LEDUC (STREMHO, IRHS Angers), J. CLOTAULT (GDO, IRHS Angers), C. RIZZON (LaMME, Univ. Evry)

PI : C. LANDES